Alright, so this is like ten thousand tiny details that add up to a specific "feel," but there are specific examples. Remember the shot in the first episode where the camera focuses on a lizard, follows it along a branch, and then slowly refocuses on the approaching caravan? That's a scene-setting trick that's really common in Hollywood, but much less so in anime - anime much more often uses a few small establishing shots from different angles, which is a trick that's actually common to both manga and Japanese film. Or the shot where blood splatters on the "camera's eye" near the end of the first episode - that's a very "modern Hollywood" trick, used to create a kind of artificial immediacy. Or even just the "hero realizes monster is really scary, camera tracks him running away with the monster directly in the background" from the second episode's Goat Fight. Or the show's love of big, dramatic zooms - Favaro on the chair in the first episode, the approaching army in the second. The show's framing uses a type of bombast very typical of many Hollywood movies.

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This also applies to both the use of animation and the details of storytelling. The mechanics of Favaro's "shit, I really have a tail" scene from the second episode. That little "this apple is a sign of my love" bit from the first episode, along with the entire role of those three comic relief thugs. It's a bunch of little things.