Ask @swisstemples:

Hey I'm a big fan of what you are doing who actually happens to be a student at UPenn, where Cotsarelis works. I bet there is a good chance I could get a coffee chat or lunch with him if I reached out. Are there any questions that would be worth asking?

Haha none that he's going to answer, I've already had people ask him questions on my behalf and he brushed them off saying he's not allowed to comment on it. Maybe you could get some interesting documents instead?

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Dear Swiss, I would like to ask that is Tubzy responsible for the approval of accounts in PHG? I've got the invitation code and I am waiting for approval since 2-3 weeks :(

Tubzy just does the invitation process and first screening. Approval is done by admin. He's been at the world hair congress and just returned. It might go a bit quicker now. Keep in contact with tubzy.

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You've previously mentioned that when you have topical pge2 you could in theory use cox inhibitors. Doesn't this mean that you can use for example resveratrol as long as you use castor oil?

No because castor oil is not real pge2. It mimics a quarter of its effect. Real pge2 cascades into pgf2a afterwards. I would not consider cox inhibitors. But if you feel like experimenting, why not. With castor you will at least have one fourth of pge2 still that's better than nothing,

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Are there any other ways to lower pgd2 except from taking sulfasalazine? And did you get any results when you were using resveratrol?

Nothing really profound yet. We've found a few substances but they're all pretty weak. Topical micronized sucra might be an alternative but it's a bitch to find. Hard to say, I used resveratrol before the hair growth set in. So, who knows? I don't think it did. Some studies show it can inhibit pge2. Maybe it was one of the reasons I only started to grow after I dropped it. We can only speculate.

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Hey, i saw your progress and it looks great, congrats..But can you send me a list what do you use now, i read your blog but i dont understand what does ru,pgd2,pge2 and that kind of stuff mean? Please tell me..I ordered Minox rogaine foam 5%now and derma roller i have coster oil what do i need more?

Thanks. Well I can't really explain that to you it takes hours and days to read up on that stuff. RU is an anti androgen, pgd2 is the hair killing prostaglandin and pge2 is one of the most beneficial prostaglandins.
Check the ghetto protocol list for stuff you could add to your regime.

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Can you please name some reliable sources to buy the ingredients in the section "What to buy and use"? Also - do you actually burn the areas to sunburn once a week? Wouldn't that be potentially harmful in the long run? Thanks, you rock.

You can find most of it on ebay, inhousepharmacy and owndoc.
Yes I do and yes you're not supposed to do it forever. Sticking to UVB makes it less bad than a real sunburn.

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Swiss, thank you very much for all you have done for us! Can you clarify something to me? Whats exactly the role of sun exposure in hair processes? Is it something related to PGD2/PGE2 ballance, right? The net effect favor us or not? Thanks!!!

Sure. Sun exposure itself doesn't do much but sunburns induce a very strong release of prostaglandins. Here's one for example, there are many more. Also if you want to do sunburns you want to combine it with sulfasalazine.
http://www.ncbi.nlm.nih.gov/pubmed/7287956

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Hey Swiss! Do you think there is a major difference between taking Seti orally vs. topically? Rumors say if swallowed 50% go down the sink because of first pass effect. Do you think if taken orally, its bioavailability is high enough to make it to the follicle in relevant quantities? Thanks! :)

It's not a rumor, I've said that after studying the setipiprant papers. It's indeed true that 50% of seti gets pissed out when taken orally. Furthermore it will get spread throughout your entire body. Since seti is a receptor blocker it makes more sense to use it topically.

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Swiss, I am one of the greatest coffee junkies I've ever met. Drinking huge amounts of coffee every day is one of the biggest pleasures in my life. Do you think I should reconsider this habit?

Well systemic caffeine is not such a big deal. Aspirin is way worse. No I don't think it's enough to affect your hair. If you truly believe you're close to OD'ing on coffee and it does affect your hair then try a week without and see how it goes. In my opinion it probably won't be different.

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Hi Swiss. Great respect to you, amazing work! My question is about a way to diminish the suffering from hair loss: beard. Can you give some advice to the patchy beard fellas? Would some form of topical adenosine help? If minox hasn't the skin destroying effect I would use it, since it works...thks!

Hey, thanks. You LOSE hair on your beard or you never grew it there to begin with? Adenosine only thickens the hair follicle diameter it's best for diffuse hair loss. Oral/topical castor will thicken it as well but to grow more beard hairs you need androgens.

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