@igotamatch#7 🇬🇧

igotamatch

Ask @igotamatch

Sort by:

LatestTop

Previous

Hope you all have a wonderful day!Smile and say hello to a stranger today!

I NEVER say HELLo ; I always say "HALLO" , as in "hallo to our crarft" (give us this day , some of your manah , for this dessert is a savanah !"
Today i said "HALLO" to many stranger ; & they're no longer strangers ! !
Now , what could be stranger than that ?
. . . perhaps this encounter of the seventh kind ~ take a looky & listen , for ye shall not be disappointed >>>>
https://www.youtube.com/watch?v=PqANJGh3TYMigotamatch’s Video 135518348410 PqANJGh3TYMigotamatch’s Video 135518348410 PqANJGh3TYM

If the world is a stage, where does the audience sit?

you've asked this B4 ; it is wrong that someone senile is posing questions to young & often vulnerable people .

Does time really heal all wounds?

Depends in the on the wound ; & the healing available ;
I've currently got a 24" slash , curved across my belly , held together by staples , from 22 days ago ; alarmingly , last night it spreng a leak ! & peritanial fluid gushed forth . . . . i had just taken a dump , was doing what humans do thereafter (personal hygiene) , when i heard a pripping sound . . . . near repeated what i had just done !
used an entire kitchen roll letting it drain . . . so see consultant 2moz ; narrowly avoided another trip to hosp. by resisting panic & calling it in ;
.
The other kind of wounds , i have from 20yrs ago . . . . . they will never heal , for they were crimes against my children , who were little more than babies . . . .
.
PLEASE listen . . . . to the colour of my wounded heart >>>
https://www.youtube.com/watch?v=DNCx7LDv7Ngigotamatch’s Video 135507414650 DNCx7LDv7Ngigotamatch’s Video 135507414650 DNCx7LDv7Ng

View more

igotamatch’s Video 135507414650 DNCx7LDv7Ngigotamatch’s Video 135507414650 DNCx7LDv7Ng

Related users

Who in your opinion is the best quarterback in the past 25 year?

I'm proud to say , i know nothing of these things !!! . . Soz to be to be such a disappointment ;
. . . it's Bruin's feeding time !!

If the food can be made in the oven or microwave, which do you choose and why?

I would rarely cook from scratch in microwave , because it's so easy to destroy food , especially if it does not have a high enough water content ; microwaves don't actually heat , neither by conduction , nor by convection , directly ; rather the radio-active micro-waves agitate the hydrogen in the h2o , causing them to give of / emit heat radiation ;
so , for example if you try to cook a piece of meat solo , ie not fully immersed in a water based sauce or jus , you will rapidly dehydrate the cells in the meat , utterly destroying it & making it inedible !
Having said that , i'm off to microwave a very generous portion on my extra special Mediteranian stew !!! yummy ! Want some ? xx

What is "CRISPG"?

. . . the answer starts below ; & soz i got it wrong , i thought it was the same as the move to make disease vectors extinct through infertility . . . But , it's different , it actually changes them (eg. mosquitoes) genetically , to render them incapable of carrying the virus / bacterium , & thus incapable of infecting people !!!!
. . . so , part 4 >>
.
The specificity of CRISPR-based immunity in recognizing and destroying invading viruses is not just useful for bacteria. Creative applications of this primitive yet elegant defense system have emerged in disciplines as diverse as industry, basic research, and medicine.
.
What are some applications of the CRISPR system?
.
The inherent functions of the CRISPR system are advantageous for industrial processes that utilize bacterial cultures. CRISPR-based immunity can be employed to make these cultures more resistant to viral attack, which would otherwise impede productivity. In fact, the original discovery of CRISPR immunity came from researchers at Danisco, a company in the food production industry [2,3]. Danisco scientists were studying a bacterium called Streptococcus thermophilus, which is used to make yogurts and cheeses. Certain viruses can infect this bacterium and damage the quality or quantity of the food. It was discovered that CRISPR sequences equipped S. thermophilus with immunity against such viral attack. Expanding beyond S. thermophilus to other useful bacteria, manufacturers can apply the same principles to improve culture sustainability and lifespan.
.
In the Lab
Beyond applications encompassing bacterial immune defenses, scientists have learned how to harness CRISPR technology in the lab [6] to make precise changes in the genes of organisms as diverse as fruit flies, fish, mice, plants and even human cells. Genes are defined by their specific sequences, which provide instructions on how to build and maintain an organism’s cells. A change in the sequence of even one gene can significantly affect the biology of the cell and in turn may affect the health of an organism. CRISPR techniques allow scientists to modify specific genes while sparing all others, thus clarifying the association between a given gene and its consequence to the organism
.
Rather than relying on bacteria to generate CRISPR RNAs, scientists first design and synthesize short RNA molecules that match a specific DNA sequence—for example, in a human cell. Then, like in the targeting step of the bacterial system, this ‘guide RNA’ shuttles molecular machinery to the intended DNA target. Once localized to the DNA region of interest, the molecular machinery can silence a gene or even change the sequence of a gene (Figure 2)! This type of gene editing can be likened to editing a sentence with a word processor to delete words or correct spelling mistakes. One important application of such technology is to facilitate making animal models with precise genetic changes to study the progress and treatment of human

View more

Have you heard of 'CRISPR' ? . What are your thoughts & feelings on . . .etc. . (i'm think in the context of making disease vectors extict ; like mosquitoes).. . . . . definition to follow !

igotamatch’s Profile Photoigotamatch
Bring it on ; make them all extinct ; look at all the misery , & suffering , & bereavement the little shits have caused & are causing ; & the latest misery , indeed atrocity being wreaked in south America , is for babies to be born without a brain - what a nightmare ,.
So ,why be sentimental about such fiendish pest >>.WIPE 'EM OUT , END THE MISERY !
.
CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat. This name refers to the unique organization of short, partially palindromic repeated DNA sequences found in the genomes of bacteria and other microorganisms.31 Jul 2014 .
.
CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat. This name refers to the unique organization of short, partially palindromic repeated DNA sequences found in the genomes of bacteria and other microorganisms. While seemingly innocuous, CRISPR sequences are a crucial component of the immune systems [3] of these simple life forms. The immune system is responsible for protecting an organism’s health and well-being. Just like us, bacterial cells can be invaded by viruses, which are small, infectious agents. If a viral infection threatens a bacterial cell, the CRISPR immune system can thwart the attack by destroying the genome of the invading virus [4]. The genome of the virus includes genetic material that is necessary for the virus to continue replicating. Thus, by destroying the viral genome, the CRISPR immune system protects bacteria from ongoing viral infection .
.
Interspersed between the short DNA repeats of bacterial CRISPRs are similarly short variable sequences called spacers (FIGURE 1). These spacers are derived from DNA of viruses that have previously attacked the host bacterium [3]. Hence, spacers serve as a ‘genetic memory’ of previous infections. If another infection by the same virus should occur, the CRISPR defense system will cut up any viral DNA sequence matching the spacer sequence and thus protect the bacterium from viral attack. If a previously unseen virus attacks, a new spacer is made and added to the chain of spacers and repeats .
.
The CRISPR immune system works to protect bacteria from repeated viral attack via three basic steps [5]:
Step 1) Adaptation – DNA from an invading virus is processed into short segments that are inserted into the CRISPR sequence as new spacers.
Step 2) Production of CRISPR RNA – CRISPR repeats and spacers in the bacterial DNA undergo transcription, the process of copying DNA into RNA (ribonucleic acid). Unlike the double-chain helix structure of DNA, the resulting RNA is a single-chain molecule. This RNA chain is cut into short pieces called CRISPR RNAs.
.
Step 3) Targeting – CRISPR RNAs guide bacterial molecular machinery to destroy the viral material. Because CRISPR RNA sequences are copied from the viral DNA sequences acquired during adaptation, they are exact matches to the viral genome and thus serve as excellent guides.
.
The specificity of CR

View more

?Have you ever donated blood? Would you? Do you know your blood type?

i used to all the time ; before i got kidney failure ; even now with a new kidney , i may never ever again , because immunosuppressed ffor anti rejection . .
. . . but my heart liver lungs spleen , are in stunning amazing condition , coz maintained super-fit throughout ; ran 8 miles every day with madog !
>>on the organ donner data base
. . . . so , I will live again !!!! xx
. . oh ! & o-negative ; rare (5% of people) universal donor . What a waste .
Liked by: Zahid Jutt

"Keep your face to the sunshine and you cannot see a shadow." ♡♥See recent please!♥♡

. . already have , dear , sweet Dafni . . . . 3 days ago ! you're falling behind ! LMBO !!! xxx
Keep your face to the sunshine and you cannot see a shadow See recent please

How is the weather where you is?

. . . grey , calm & bright ; surprisingly mild , after a hard frost last night & snow @ last weekend . . . . & there are birds (jackdaws) shagging in the tree-tops outside my upstairs window . . . . enjoy while you can , lil' burds , for the day cometh when the sparrow hawk (or maybe even an HARRIS hawk) , will swoop down & scoff all your babies . . .
How is the weather where you is
Liked by: Victoria Zahid Jutt

Do politics interest you?

YES !
. . . . Scottish Nationalist ; an strong independent Scotland , free from the feeble-minded westminster imbeciles , who are hell-bent in dragging us out of europe & are climate-change-deniers . . . . within a strong , united European Super State !

Good morning!Do you like coffee?If so how do you take your coffee?If you don't like coffee what is your favorite flavor of gum?

i adore coffee . . . .
I'm not really here , this scottish afternoon , coz i've not yet had my amazing home ground & brewed coffee ; & i'm not having yet , for i'm going 4 more sleep - I didn't get to bed till 7a.m. , this morning , because of a problem . . . . so just got up to let my dog in the garden & give her , her medicine . . . . . & me mine ! LMBO !
. . . SOOOO , i'm off 4 a 2hr knap , then that luxuious delectable coffee , un contaminated by sweetner nor lactose , just some milk-free whitener (only nestle's will do!) ~& it's super-strong
". . . I get up & make the coffee , it must be love , it must be love . . . "
.
https://www.youtube.com/watch?v=6GywKzwoAd4igotamatch’s Video 135500644986 6GywKzwoAd4igotamatch’s Video 135500644986 6GywKzwoAd4

q4) Which singer starred in the televison documentary From Riches to Rags?

I do not have a clue ; is it her ? (i really tried)
lili allen ?
q4  Which singer starred in the televison documentary From Riches to Rags

q2) Which Irish novelist was personal assistant of actor Henry Irving and business manager of the Lyceum Theatre in London?

. . . So , t'was Bram Stoker , t' be sure nigh , so it was , so it was , right enough , who else could it ave been , when it was himself . . . .
Bram Stoker. Abraham "Bram" Stoker (8 November 1847 – 20 April 1912) was an Irish author, best known today for his 1897 Gothic novel, Dracula. During his lifetime, he was better known as the personal assistant of actor Henry Irving and business manager of the Lyceum Theatre in London, which Irving owned.

q3) How do i wake up Colin without giving him a heart attack? or scaring him half to death?

put on death metal , very very quietly , & gradually , very very slowly , pausing occasionally , turn it up . . . . . & up . . . . . && up & up && up &up n up n up . . . till the windows are shaking !
.
this is not death metal , but it's turn it up
TURN IT UP
(the voices i hear , are audible to everyone , everyone but me , turn it up . . . )
.
https://www.youtube.com/watch?v=2rqbqwNK3noigotamatch’s Video 135493823098 2rqbqwNK3noigotamatch’s Video 135493823098 2rqbqwNK3no

On a scale of 1-10 rank your maturity.I register as a negative 4.

minus a couple of million , tonight . . . . kryste , is 0508hrs

* I'd be glad to read about a situation when you felt proud of yourself! *

. . when Gorbachev 's chef requested my product for the Duma banquet !
. . . when i rescued 2 people from their car on it's roof , down a steep enbankment in a snow storm ; a lone pig who got through was so grateful ; he was scared ! my pre-school age 3 kids were outraged that their ma was cursing me saying "why does HE always have to get involved" hell , we had a brand new car & full tank . . . . they chose me @ the divorce . . . have grown into incredible moral people , of whom i am more proud than anything else in the world .
what i'm NOT proud of is when i resuscitated a dead friend & he stayed dead . . .

What does your aura look like?

none of your business . You're just looking for an excuse to bann me again . . . get thee hence , o thou enemy of my soul . . .
What does your aura look like

q1) Claire Richards was the lead singer in which dance-pop group?

IDK ; but i think she got tired of dancing . . .
q1 Claire Richards was the lead singer in which dancepop group

?What are your favorite pastries? (also, doing number question thing: http://ask.fm/angie_caroline/answer/136437672608)

tonight , after my main course i ate the 2nd half of a carrot cake . . .
while i'm not so big on pastry , i can quite enjoy a well made pastry .
there's a rather down to earth scottish savory pastry , meat based called a bridie .
"Forfar Bridies" are the best in the world - so long as it from a trad baker or butcher , & hard to find ; for Forfar has few traditional establishments left as with everywher , these days , & has those dreadful chain plastic bakeries , "Gregg's"
ther'es an old established family butcher in my town (Hawick) . . . . . they makemake "world champion bridies" , but i so rarely get them for they are sooooooo-salty ! & , I'M NOT THAT BIG ON PASTRIES !!! x so , do the number question thing ???
http://ask.fm/angie_caroline/answer/136437672608)

Next

Language: English