In largely depends on the setting, situation, and people involved. I always revise myself, check for vulnerability, and reflect on my actions to see if there was anything I did that may come back and be a pain in my neck.

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I usually don't embrace the vulenrability of others unless the situations call for it. Toying with someone's weakness is a little too easy and predictable, that's why they hide it. In order to manipulate a person well, you have to know what hurt the most, and that's something they never show unless you observe them carefully.