When food spoils, it goes bad. It becomes rotten:

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- If you don't put milk in the refrigerator, it will spoil.

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When you spoil a person (or animal), it means that you give them whatever they want or give them really nice things:

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- Henry's grandmother still spoils him with expensive birthday presents; last year, she bought him a car.
- Nan spoils her nephews and nieces by taking them to Disneyland every summer.

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Lastly, "spoil" can be used as a synonym for "ruin":

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- Nan spoiled the surprise by telling Peter that we bought him a new iPad.
- Bad weather spoiled our spring break.